60,000 Brits could be at higher risk of cancer without realizing it
Around 60,000 Brits could be at higher risk of cancer but not realize it, a charity has warned. These are individuals who have previously been tested for the BRCA genetic fault and were told their results were negative. However, recent scientific advances have identified more mutant genes that can increase a person's risk of hereditary cancer. The charity, National Hereditary Breast Cancer Helpline, is urging those who were previously told they were negative for faulty BRCA genes to see their GP.
New tests available to check cancer risk
The BRCA genes, known for their association with Angelina Jolie, can increase the risk of breast, ovarian, and prostate cancer if they are faulty. People with a family history of breast cancer were tested for BRCA1, BRCA2, and TP53 before 2018. However, the NHS is not currently inviting those who previously tested negative for BRCA1 and BRCA2 for another test. The charity warns that these individuals may still be at risk without realizing it. This includes Loose Women star Coleen Nolan and around 60,000 others with a family history of the disease who could be eligible for new tests to check their cancer risk.
Unaware of new test
Coleen Nolan, who comes from a family haunted by cancer, revealed that she was not aware of the new test. Her family has been affected by skin cancer, with Coleen becoming the fourth sister to be diagnosed in 2023. She expressed her intention to get tested after finishing her current tour. Coleen had previously tried to get a BRCA1 and BRCA2 test but was not tested for anything else after her sisters received negative results.
Genes and cancer risk
Some forms of cancer, including breast, ovarian, colorectal, and prostate cancer, can be strongly influenced by genes and run in families. For example, out of every 100 women with a BRCA1 gene mutation, 65 to 85 will develop breast cancer in their lifetime and 40 to 63 will develop ovarian cancer. The NHS advises individuals who have a family history of cancer and are concerned about their risk to speak to their GP.
Advocacy for genetic testing
Wendy Watson MBE, the founder of the National Hereditary Breast Cancer Helpline, has dedicated her life to raising awareness of genetic testing for cancer. She was the first person in the UK to undergo a preventative mastectomy after testing positive for a genetic risk. Wendy and her daughter, Becky, are now working to spread awareness and encourage individuals to know their risk and take preventive measures.
