Research Shows Fasting-like Diets Could Reverse Ageing and Protect Against Diseases
A recent study suggests that fasting-like diets could potentially reverse the ageing process and provide protection against serious diseases. Participants following a fasting-mimicking diet (FMD) were found to have lowered their biological age by an average of two and a half years, along with reducing the risks of age-related conditions like cancer, diabetes, and heart disease. Researchers attribute these benefits to decreased insulin resistance, liver fat, and slower immune system ageing.
How the FMD Works and its Impact on Health
The Fasting-mimicking diet (FMD) is a five-day regimen high in 'healthy' unsaturated fats and low in overall calories, protein, and carbohydrates. Designed to replicate the effects of a water-only fast, the diet aims to trigger the release of enzymes and chemicals associated with longevity. Participants in clinical trials followed three to four monthly cycles of the FMD, consuming plant-based soups, energy bars, drinks, and tea portioned over five days, along with a high-nutrient supplement. Results showed reduced risks of diabetes, improved immune system function, and decreased abdominal and liver fat among FMD participants compared to a control group following a normal or Mediterranean-style diet.
'Short-term and Achievable' Benefits of the FMD
Statistical analysis revealed that participants following the FMD reduced their biological age by an average of two and a half years, regardless of weight loss. This measure reflects how well cells and tissues function rather than chronological age. The study suggests that the FMD has rejuvenating effects on the immune system, making it a potentially short-term, periodic dietary intervention to reduce disease risk and enhance overall health without drastic lifestyle changes. Researchers hope these findings will prompt healthcare providers to recommend the FMD to patients with higher disease risks and those seeking age-related benefits.
Previous research by the team has shown that periodic FMD cycles may promote stem cell regeneration and alleviate chemotherapy side effects, while mouse trials indicated benefits for reducing dementia symptoms. The recent study, however, is the first to highlight the FMD's effects on insulin resistance, liver fat, immune system ageing, and biological age.
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