New Treatment Breakthrough for Leukaemia: Scientists Target Cancer Cells' Oxygen Sensors


New Treatment Breakthrough for Leukaemia: Scientists Target Cancer Cells' Oxygen Sensors

Promising New Treatment for Leukaemia

Scientists have announced a breakthrough in the treatment of leukaemia, a form of blood cancer that has seen little progress in over 30 years. By targeting oxygen sensors that cancer cells use to survive and multiply, researchers believe they may have found a way to combat acute myeloid leukaemia (AML) and potentially other types of cancer in the future.

New Hope for AML Patients

AML is a particularly aggressive form of blood cancer that affects thousands of people in the UK each year, with a high mortality rate. Current treatments like chemotherapy and bone marrow transplants often have limited effectiveness and can come with serious side effects. However, this new approach offers a promising alternative for patients who may not respond well to traditional therapies.

Potential for Future Treatments

Professor Kamil Kranc, the study leader at The Institute of Cancer Research in London, expressed optimism about the research findings, stating that targeting oxygen response mechanisms in cells could open up new avenues for treating leukaemia. The study's results, published in the journal Nature Cancer, have shown promising results in lab trials on mice and human cells.

Exciting Developments in Cancer Research

The team behind the study, which includes researchers from Oxford University and Cancer Research UK, is encouraged by the potential of using existing drugs to disrupt cancer cell growth. By turning off enzymes that support tumour growth in response to oxygen levels, the researchers believe they can develop more effective and affordable treatments for leukaemia and potentially other solid tumours.

Looking Ahead to Clinical Trials

Prof Kristian Helin, chief of the Institute of Cancer Research, highlighted the significance of the research in understanding how cancer cells utilize signals within the body to thrive. The next step for the research team is to progress towards clinical trials to further explore the effectiveness of this novel treatment approach.