Mum-of-three, 42, with ‘chest infection’ becomes first person in the world to be diagnosed with ultra-rare cancer

A 42-year-old mother of three, Alison Varley, initially thought to have a chest infection, has made medical history by becoming the first person in the world to be diagnosed with an ultra-rare form of cancer.

The unexpected diagnosis

Alison, from Ossett, West Yorkshire, sought medical attention after struggling to breathe, only to be misdiagnosed with a chest infection. Despite treatment with antibiotics, her condition did not improve, leading to further investigations that revealed she had goblet cell carcinoma, a type of cancer never seen before.

According to Alison, her cancer's genetic makeup is entirely unique, making it challenging for doctors to devise an effective treatment plan. She underwent immunotherapy initially, but the treatment unexpectedly caused her cancer to grow.

A challenging journey

Alison's cancer originated in her appendix before spreading to her bowel, ovary, and rectum. She has undergone various treatments at different hospitals, including St James's University Hospital in Leeds, The Christie in Manchester, and Basingstoke and North Hampshire Hospital.

After a brief pause in treatment due to concerns about disease progression, Alison recently started chemotherapy, which she will continue for the next three months. Despite the uncertainty and fear surrounding her treatment, she remains determined to fight the disease for the sake of her children.

A community's support

Alison's friend, Adam Billington, launched a fundraiser to assist the Varley family with everyday expenses during this challenging time. The generosity of donors has provided crucial support, allowing Alison to focus on her health and her children.

Expressing her gratitude for the outpouring of support, Alison shared her heartfelt appreciation for the donations that have helped ease the family's financial burden. She remains hopeful for the future, cherishing each moment with her loved ones as she navigates this unprecedented medical journey.