Triggering a "Time Bomb" in Cancer Cells
Scientists have made a groundbreaking discovery in cancer treatment that could revolutionize how tumors are targeted. The new method involves triggering a "time bomb" in cancer cells, opening them up to new treatments.
Identifying a Critical Epitope for Cytotoxic Fas Signaling
Researchers from the US have identified a receptor on the cells' blood vessels called Fas (or CD95), which, when triggered by the right antibody, causes the death of the cell. Previous attempts to target this receptor have failed, but now scientists have identified a critical epitope for cytotoxic Fas signaling.
Potential for Developing Therapies That Specifically Target Fas on Tumors
This breakthrough could pave the way for developing therapies that specifically target Fas on tumors. The treatment could activate Fas to destroy cancer cells and make them more receptive to CAR T-cell immunotherapy, resulting in a one-two punch against tumors.
Study Conducted on Mice
The study, published in the journal Cell Death & Differentiation, was conducted on mice.
Improving Cancer Treatment and Saving Lives
This discovery has the potential to improve cancer treatment and save lives.
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