Aspirin and Immune Response
An aspirin a day can 'weaponise' parts of the body’s immune system to help it destroy bowel cancer cells. Research suggests that daily aspirin use could assist in fighting bowel cancer by boosting certain aspects of the body’s immune response against cancer cells.
Protective Effects of Aspirin
Previous studies have indicated that long-term aspirin use may reduce the risk of bowel cancer development and progression. The common painkiller, also known as acetylsalicylic acid, belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs).
Research Findings
A recent study published in a journal revealed that aspirin can have a protective effect against cancer by enhancing specific parts of the body’s immune response to cancer cells. Researchers found that aspirin could increase the expression of a protein called CD80 on certain immune cells, improving their ability to detect proteins associated with tumors.
Impact on Bowel Cancer Cells
Analysis of tissue samples from patients who took aspirin daily showed that their bowel cancer had spread less into their lymph nodes. Additionally, there was a higher concentration of immune cells in their tumors compared to samples from non-aspirin users.
Conclusion
The study suggests a complementary mechanism of cancer prevention or therapy with aspirin, aside from its anti-inflammatory properties. Aspirin users with rectal cancer also demonstrated higher CD80 expression in healthy rectal tissue, indicating a potential boost to the immune system’s cancer surveillance abilities.
Research also implies that aspirin absorption in the colon plays a crucial role in its effectiveness against colorectal cancer. However, it is essential to consult a doctor before starting a daily aspirin regimen, as improper use may lead to adverse effects.
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